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. 2015 Sep 25;7(1):240–245. doi: 10.1039/c5sc03110a

Table 2. Rh-catalyzed alkylation of aromatic amide 1a with α,β-unsaturated γ-butyrolactones 2b–2h a , b .

graphic file with name c5sc03110a-u2.jpg

aReaction conditions: amide 1 (0.3 mmol), lactone 2a (0.9 mmol), [RhCl(cod)]2 (0.015 mmol), K2HPO4 (0.075 mmol), toluene (1 mL), at 160 °C for 24 h.

bIsolated yields. The number in parentheses denotes the ratio of cis and trans isomers.

cThe reaction was run for 12 h.

dKOAc was used in place of K2HPO4.