Table 2. Rh-catalyzed alkylation of aromatic amide 1a with α,β-unsaturated γ-butyrolactones 2b–2h a , b .
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aReaction conditions: amide 1 (0.3 mmol), lactone 2a (0.9 mmol), [RhCl(cod)]2 (0.015 mmol), K2HPO4 (0.075 mmol), toluene (1 mL), at 160 °C for 24 h.
bIsolated yields. The number in parentheses denotes the ratio of cis and trans isomers.
cThe reaction was run for 12 h.
dKOAc was used in place of K2HPO4.