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. 2018 May 1;34(4):360–364. doi: 10.1089/jop.2017.0080

Table 1.

The Active Ingredient and Preservative in Each of the 6 Artificial Tear Products

Artificial tear product Active ingredient Preservative
HA1 HA 0.1% and CMC Stabilized oxychloro complex
HA2 HA 0.18%
HA3 Trehalose 3% and HA 0.15%
HA4 HA 0.15%
HA5 HA 0.1% provided in the COMOD device
HPG/HA HPG, HA 0.1%, and demulcents Polyquad (polyquaternium-1) 0.001%

CMC, carboxymethylcellulose; HA, hyaluronic acid; HA1 (Optive Fusion™; Allergan Limited, United Kingdom); HA2 (Vismed®; TRB Chemedica International S.A., Switzerland); HA3 (Thealoz Duo®; Thea Pharmaceuticals Limited, United Kingdom); HA4 (Hyabak®; Thea Pharmaceuticals Limited, United Kingdom); HA5 (Hylo-Comod®; URSAPHARM Arzneimittel GmbH, Germany); and HPG/HA (Systane® Hydration; Alcon Research Ltd., Fort Worth Texas); HPG/HA, hydroxypropyl guar/hyaluronic acid-containing dual-polymer lubricant formulation.