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SB suppresses the inflammation in TNBS-induced mice.
(A-B) Expression of the pro-inflammatory cytokines TNF-α and IL-6 in colon tissue homogenate (n = 4). (C) H&E staining of colon tissue from TNBS- and SB-treated WT and GPR109a−/−mice−, magnification shown is 4 ×, and the scale bar represents 100 μm (n = 4). (D) Total damage score of TNBS- and SB-treated WT and GPR109a−/− mice (n = 8–12).
