Table 1.
Demographic Characteristics and Participant Outcomes
| Totala | TB-HIV | HIV | p-value | |
|---|---|---|---|---|
| (n = 32) | (n = 17) | (n = 15) | ||
| Female | 62% (20/32) | 47% (8/17) | 80% (12/15) | 0.08^ |
| Median Age (range) | 32 [18–53] | 30 [18–52] | 36 [24–53] | 0.43^^ |
| Initial CD4+ (cells/μL) | 50 [4–105]b | 23 [4–105] | 67 [11–96] | 0.15^^ |
| Time to ART start (days) | 14 [6–80]c | 14.5 [12–80] | 12 [6–51] | 0.08^^ |
| IRIS | 20% (5/25) | 45% (5/11) | 0% (0/14) | 0.13^ |
| Alive at 6 months | 75% (24/32) | 59% (10/17) | 93% (14/15) | 0.03^ |
aDemographic data available for 32 study participants. Whole blood RNA-Seq analysis done for 33 participants
bThe initial CD4 count for 2 participants was 103 and 105 cells/μl; however when repeated for the study, the counts were less than 100 cells/μl
c19 observations
^p-value calculated by Fischer’s exact
^^p-value calculated by Wilcoxon rank sum test
Age given is median age, range is entire range of ages. CD4+ range is entire range of CD4+ T cell counts