Table 3.
Preserved systolic function in Nrf2 KO mice as measured by cMRT (mean ± SD, n = 5 each).
| Parameter | Units | WT mice (mean ± SD) | Nrf2 KO mice (mean ± SD) | p value |
|---|---|---|---|---|
| BM | (g) | 35.39 ± 2.55 | 33.41 ± 2.32 | 0.228 |
| Age | (d) | 219.50 ± 26.48 | 217.50 ± 28.49 | 0.911 |
| HF | (min−1) | 547.42 ± 49.56 | 519.17 ± 26.36 | 0.287 |
| EDV | (μl) | 52.03 ± 7.61 | 51.41 ± 5.80 | 0.888 |
| ESV | (μl) | 15.33 ± 3.98 | 15.89 ± 2.42 | 0.792 |
| SV | (μl) | 36.70 ± 4.38 | 35.52 ± 4.11 | 0.668 |
| EF | (%) | 70.86 ± 3.99 | 69.10 ± 2.81 | 0.439 |
| HZV | (ml/min) | 19.98 ± 2.17 | 18.47 ± 2.49 | 0.330 |
| m (D) | (mg) | 112.17 ± 16.00 | 119.62 ± 8.54 | 0.380 |
| rel. m | (mg/g) | 3.19 ± 0.56 | 3.59 ± 0.23 | 0.177 |
| dmitt (D) | (mm) | 1.09 ± 0.06 | 1.07 ± 0.06 | 0.646 |
| dmitt (S) | (mm) | 1.59 ± 0.10 | 1.60 ± 0.07 | 0.844 |
| WVmitt | (%) | 145.35 ± 7.31 | 149.24 ± 9.58 | 0.487 |