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. 2018 Apr 30;2018:3231647. doi: 10.1155/2018/3231647

Figure 5.

Figure 5

Astragalosides decreased the levels of collagen-related indicators and α-SMA in liver tissues. (a) By assay of ELISA and real-time PCR, AST was found to decrease the expression of COL-I induced by CCL4 in rats. (b-c) By assay of ELISA and real-time PCR, AST was also found to decrease the expression of COL-III and α-SMA. AST: astragalosides; LY-364947: TGF-β receptor 1 inhibitor. The values presented are the means ± SD (n = 10 in each group). P < 0.05 and ∗∗P < 0.01 versus control group; #P < 0.05 and ##P < 0.01 versus model group (CCL4).