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. 2018 Apr 30;2018:6106051. doi: 10.1155/2018/6106051

Figure 2.

Figure 2

Fed plasma glucose over time in low (a) and high (b) fat-fed mice treated with three consecutive once-daily doses of vehicle or 30, 50, or 75 mg/kg STZ. 16-hour fasted plasma glucose (c) and insulin (d) levels four weeks after vehicle or STZ treatments. Treatment groups are denoted as follows: low fat—vehicle, open circles (n = 4); low fat—30 mg/kg STZ, open squares (n = 4); low fat—50 mg/kg STZ, open triangles (n = 4); high fat—vehicle, closed circles (n = 4); high fat—30 mg/kg STZ, closed squares (n = 3); high fat—50 mg/kg STZ, closed triangles (n = 6); and high fat—75 mg/kg STZ, × (n = 3). Data are means ± SEM. ∗p < 0.05 versus high fat—vehicle.