Figure 3.

(a) Fluorescence SVD amplitude for Photofrin in tissue-simulating phantom experiments with different optical properties (μ_a = 0.1 – 0.9 cm⁻¹ and μ_s’ = 5 – 24 cm⁻¹) but constant Photofrin concentration of 3mg/kg. Photofrin SVD amplitudes were corrected for optical properties using Eq. (3) to obtained corrected SVD amplitude, A_p,ref (b) Fluorescence spectra of Photofrin at concentrations ranging from 0.0625 mg/kg to 9 mg/kg in tissue simulating phantom with μ_a,ref = 0.3 cm⁻¹ and μ_s,ref’ = 9.6 cm⁻¹ and (c) Photofrin concentration calibration curve.