Table 1.
Baseline characteristics of study participants at enrolment
| Pyronaridine–artesunate (n = 101) |
Artemether–lumefantrine (n = 96) |
|
|---|---|---|
| Male sex, n (%) | 53 (52.5) | 48 (50.0) |
| Mean age, years (SD) [range] | 6.9 (2.9) [1.6–12] | 6.4 (3.3) [0.9–12] |
| Age category, years, n (%) | ||
| ≤ 1 | 0 | 2 (2.1) |
| > 1 to < 5 | 31 (30.7) | 31 (32.3) |
| 5–12 | 70 (69.3) | 63 (65.6) |
| Mean weight, kg (SD) [range] | 23.0 (8.4) [10–44] | 22.4 (9.2) [8.5–45] |
| Mean hemoglobin, g/dL (SD) [range] | 11.8 (1.9) [6.2–15.8] | 11.9 (2.1) [6.8–16.4] |
| Mean temperature, °C (SD) [range] | 37.5 (1.2) [35.1–39.8] | 37.3 (1.2) [35.2–39.9] |
| Fever (temperature > 37.5 °C), n (%) | 53 (52.5) | 40 (41.7) |
| Geometric mean asexual parasitaemia, µL−1 (95% CI) | 24,420.6 (18,837.6–31,658.3) | 23,672.5 (18,576.2–30,167.0) |
| Gametocyte prevalence-microscopy, n (%) | 2 (1.98) | 4 (4.17) |