Table 2.
Patient referral and inclusion and exclusion in the PACE Plus trial
| Trial period | Before design modification | After design modification | Total |
|---|---|---|---|
| Number of participating GPs (number of participating practices) | 79 (26) | 96 (36) | 96 (36) |
| Referrals (number of referring practices) | 22 (12) | 9 (6) | 31 (15) |
| Exclusions (% of referrals) | 18 (82%) | 9 (100%) | 27 (87%) |
| Patient did not meet inclusion criteria | 9 | 4 | 13 |
| Intake of study medicines before inclusion | 5 | 1 | 6 |
| Pain score (NRS 0–10) < 3 | 1 | 1 | 2 |
| Specific cause of low back pain | 0 | 1 | 1 |
| Age > 60 years | 1 | 0 | 1 |
| Comorbidity/co-medication with interaction | 1 | 1 | 2 |
| Insufficient knowledge of Dutch language | 1 | 0 | 1 |
| Patient declined to participate | 9 | 5 | 14 |
| Inclusions (% of referrals) | 4 (18%) | 0 (0%) | 4 (13%) |