Table 2.
Comparison of clinicopathological factors of duodenal GISTs according to surgical procedure
| Characteristics | Limited resection (n = 200) | Pancreaticoduodenectomy (n = 77) | P value |
|---|---|---|---|
| Age | 0.782 | ||
| ≤ 60 | 101 (60.5%) | 48 (62.3%) | |
| > 60 | 66 (39.5%) | 29 (37.7%) | |
| Gender | 0.205 | ||
| Male | 100 (51.3%) | 32 (42.7%) | |
| Female | 95 (48.7%) | 43 (57.3%) | |
| Anatomical location | < 0.001 | ||
| Superior portion | 37 (19.7%) | 3 (5.1%) | |
| Descending portion | 73 (38.8%) | 52 (88.1%) | |
| Horizontal portion | 56 (29.8%) | 4 (6.8%) | |
| Ascending portion | 22 (11.7%) | 0 | |
| Tumor size | < 0.001 | ||
| ≤ 2 cm | 28 (15.1%) | 3 (4.1%) | |
| 2–5 cm | 102 (54.8%) | 25 (33.8%) | |
| 5–10 cm | 37 (19.9%) | 32 (43.2%) | |
| > 10 cm | 19 (10.2%) | 14 (18.9%) | |
| Mitotic index | < 0.001 | ||
| ≤ 5 | 144 (83.2%) | 32 (52.5%) | |
| > 5 | 29 (16.8%) | 29 (47.5%) | |
| Morphology | 0.146 | ||
| Spindle | 100 (94.3%) | 39 (86.7%) | |
| Epithelioid | 0 | 1 (2.2%) | |
| Mixed | 6 (5.7%) | 5 (11.1%) | |
| NIH risk category | < 0.001 | ||
| Very low | 23 (12.8%) | 2 (2.8%) | |
| Low | 87 (48.6%) | 15 (21.1%) | |
| Intermediate | 2 (1.1%) | 0 | |
| High | 67 (37.4%) | 54 (76.1%) | |
| Neoadjuvant therapy | 0.472 | ||
| No | 194 (97.0%) | 73 (94.8%) | |
| Yes | 6 (3.0%) | 4 (5.2%) | |
| Adjuvant therapy | 0.362 | ||
| No | 165 (82.5%) | 67 (87.0%) | |
| Yes | 35 (17.5%) | 10 (13.0%) |
GIST: gastrointestinal stromal tumor; NIH: National Institutes of Health