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. 2018 May 14;22:130. doi: 10.1186/s13054-018-2049-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Fifteen metabolites dysregulated in CAP compared to controls. a Hierarchical cluster heatmap of 15 metabolites in three groups. Row represents metabolites and column represents individual samples. Green, red and blue represent non-severe CAP (NSCAP), severe CAP (SCAP) and controls, respectively. Greater brown indicates higher relative intensity of metabolites, while light blue indicates lower intensity. b Metabolic pathway analysis of 15 metabolites changed in CAP. Node colour based on p value and node radius determined based on pathway impact values. CAP community-acquired pneumonia, DHEA-S dehydroepiandrosterone sulfate