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. 2018 May 14;22:130. doi: 10.1186/s13054-018-2049-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Three metabolites identified that can discriminate severe CAP from non-severe CAP in validation cohort. Chemical structures of three metabolites. Box–whisker plots of concentrations of three metabolites in three groups. Horizontal line represents median; bottom and the top of box represent 25th and the 75th percentiles; whiskers represent 5% and 95% percentiles. *p < 0.01, **p < 0.001. CAP community-acquired pneumonia, DHEA-S dehydroepiandrosterone sulfate, NSCAP non-severe CAP, SCAP severe CAP