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. 2018 Mar 1;16:157–168. doi: 10.1016/j.redox.2018.02.019

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© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — Ripk3 induced ROS overproduction via ER -calcium-XO signaling pathways. (n = 6/group). (A) The Ca²⁺ levels under LPS and H₂O₂ were observed by fluo-2. (B) The change of XO expression by western blot. (C) The change of XO mRNA expression by PCR. (D) ROS production was observed by DHE staining. *P < 0.05 vs WT group, ^#P < 0.05 vs the WT+LPS+H₂O₂ group.