Fig. S2.

Infection efficiency of rAAV2 and its effect on blood pressure. A, Infection efficiency of rAAV2-GFP and rAAV2-LMP10 in the retinas indicated by GFP fluorescence (green). Nuclei were counterstained with DAPI (blue). Scale bar, 50 µm. GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; RPE, retinal pigment epithelium. B, Immunoblotting analysis of LMP10 level in each group (upper). Quantitative analysis of protein intensity (lower, n = 4 mice per group). C, Measurement of systolic blood pressure in rAAV2-GFP- and rAAV2-LMP10-injected mice with or without IMD-0354 injection 3 weeks after Ang II infusion by the tail-cuff method (n = 10 mice per group). Data expressed as the mean ± SEM. *P < 0.05 vs rAAV2-GFP-injected mice infused with saline, ^#P < 0.05 vs rAAV2-GFP-injected mice infused with Ang II.