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Structure of mature cardiolipin. Cardiolipin is a unique anionic phospholipid with 4 acyl chains and a small headgroup. Mature cardiac cardiolipin contains predominantly 4 linoleic acid (18:2) acyl chains under healthy conditions. Modifications to the acyl chains of cardiolipin are common in a range of diseases and can also be modified in response to dietary intake of differing FAs.
