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. 2015 Oct 19;7(1):673–677. doi: 10.1039/c5sc03116h

Table 1. Identification of the most suitable ligand for the synthesis of 2-methoxy-1,1′-binaphthyl 8b a .

Entry Complex Protein ee b [%] TON
1 1 WT Sav 58 (R) 78
2 2 WT Sav 10 (S) 73
3 3 WT Sav 42 (R) 45
4 4 WT Sav 6 (R) 8
5 5 WT Sav rac <5
6 1 WT Avi 3 (R) 10

aReactions were carried out with 50 mM substrate in a total reaction volume 0.2 mL using 1 mol% complex 1–5 (see ESI for experimental details).

bee value determined by HPLC on a chiral stationary phase; absolute configuration assigned by comparison with literature data. WT = wild-type, Sav = streptavidin, Avi = avidin. All reactions were performed in duplicate: Δee = ±1%, Δconv. = ±5%.