(A) Three main classes of neuron-glia contacts in C. elegans. Neurons, red; glia, green. Ax, axons; Dn, dendrite. (B) The glial cell can create specialized subdomains tailored for specific neuronal partners, as evidenced by the localization of the KCC-3 ion co-transporter (blue) in the glial cell membrane exclusively adjacent to a single dendrite receptive ending.