The expression of p47phoxand p67phoxwere increased in the area surrounding Aβ inAppTg mice. p47phox (A, E) and p67phox (I, M) immunoreactivity co-localized with GFAP (B, F, J, N) and was reduced in the area surrounding Aβ (C, G, K, O) in AppTg/Cebpd-/- mice. The merged photo is shown in D, H, L and P. Coronal sections of the cortex were collected from AppTg and AppTg/Cebpd−/− mice and subjected to immunofluorescence with anti-GFAP, anti-Aβ, anti-p47phox and anti-p67phox antibodies.