Supplemental Table 4.
Echocardiographic results of arrhythmogenic right ventricular cardiomyopathy (ARVC) and control group, with a cut-off of ≥ 50, ≥ 100 and ≥ 200 ventricular premature complexes (VPC), respectively.
| Parameter | ARVC: Cut-off ≥ 50 VPC | ARVC: Cut-off ≥ 100 VPC | ARVC: Cut-off ≥ 200 VPC | ||||||
|---|---|---|---|---|---|---|---|---|---|
| ARVC (n = 45) | Controls (n = 216) | p-value | ARVC (n = 42) | Controls (n = 219) | p-value | ARVC (n = 47) | Controls (n = 214) | p-value | |
| Decreased RV function | 3 (6.7%) | 2 (1.0%) | 0.045 | 3 (7.1%) | 2 (1.0%) | 0.037 | 3 (7.7%) | 2 (1.0%) | 0.030 |
| RV dilatation | 5 (11.1%) | 4 (2.0%) | 0.012 | 5 (11.9%) | 4 (2.0%) | 0.009 | 4 (10.3%) | 5 (2.4%) | 0.039 |
| RV wall motion abnormality | 4 (8.9%) | 3 (1.5%) | 0.023 | 4 (9.5%) | 3 (1.5%) | 0.018 | 4 (10.3%) | 3 (1.5%) | 0.014 |
| RA dilatation | 3 (6.7%) | 6 (3.0%) | 0.217 | 3 (7.1%) | 6 (3.0%) | 0.186 | 2 (5.1%) | 7 (3.4%) | 0.638 |
| Aortic diameter (mm) | 19.8 ± 2.2 | 19.2 ± 3.3 | 0.313 | 19.8 ± 2.2 | 19.2 ± 3.3 | 0.285 | 19.8 ± 2.2 | 19.2 ± 3.3 | 0.345 |
| LA diameter (mm) | 33.1 ± 8.8 | 30.9 ± 7.9 | 0.146 | 33.6 ± 9.0 | 30.9 ± 7.8 | 0.066 | 33.1 ± 8.0 | 31.0 ± 8.1 | 0.181 |
| LVEF (%) | 47.8 ± 13.2 | 50.0 ± 16.5 | 0.532 | 47.5 ± 13.4 | 50.0 ± 16.5 | 0.467 | 47.0 ± 13.3 | 50.2 ± 16.4 | 0.365 |
| IVSd (mm) | 10.6 ± 1.7 | 10.3 ± 2.0 | 0.382 | 10.7 ± 1.7 | 10.3 ± 2.0 | 0.286 | 10.6 ± 1.7 | 10.4 ± 2.0 | 0.469 |
| LVIDd (mm) | 40.2 ± 5.8 | 39.5 ± 7.5 | 0.582 | 40.5 ± 5.7 | 39.4 ± 7.5 | 0.390 | 40.7 ± 5.6 | 39.4 ± 7.5 | 0.294 |
| LVPWd (mm) | 10.6 ± 1.9 | 10.8 ± 1.8 | 0.497 | 10.5 ± 1.9 | 10.9 ± 1.8 | 0.265 | 10.4 ± 1.7 | 10.9 ± 1.8 | 0.138 |
| LVIDs (mm) | 30.3 ± 7.2 | 28.5 ± 8.6 | 0.215 | 30.8 ± 7.0 | 28.4 ± 8.5 | 0.105 | 31.0 ± 7.0 | 28.4 ± 8.5 | 0.086 |
| FS (%) | 25.7 ± 0.5 | 28.4 ± 10.3 | 0.126 | 25.0 ± 9.3 | 28.5 ± 10.3 | 0.052 | 25.0 ± 9.5 | 28.5 ± 10.3 | 0.059 |
| TAPSE (mm) | 15.3 ± 4.5 | 15.5 ± 2.8 | 0.925 | 15.3 ± 4.5 | 15.5 ± 2.8 | 0.925 | 15.9 ± 4.5 | 15.2 ± 2.9 | 0.576 |
| MV E Velocity (m/s) | 0.80 ± 0.23 | 0.82 ± 0.21 | 0.625 | 0.81 ± 0.23 | 0.82 ± 0.21 | 0.830 | 0.81 ± 0.23 | 0.82 ± 0.21 | 0.830 |
| MV Deceleration time (ms) | 122 ± 29 | 127 ± 40 | 0.658 | 124 ± 29 | 126 ± 40 | 0.830 | 124 ± 29 | 126 ± 40 | 0.830 |
| MV Deceleration slope (m/s2) | 7.2 ± 3.1 | 6.4 ± 2.3 | 0.311 | 7.2 ± 3.1 | 6.4 ± 2.3 | 0.329 | 7.20 ± 3.12 | 6.44 ± 2.31 | 0.830 |
| MV A Velocity (m/s) | 0.54 ± 0.15 | 0.55 ± 0.15 | 0.678 | 0.53 ± 0.14 | 0.56 ± 0.15 | 0.474 | 0.53 ± 0.14 | 0.55 ± 0.15 | 0.329 |
| MV E/A | 1.58 ± 0.79 | 1.56 ± 0.53 | 0.880 | 1.62 ± 0.81 | 1.55 ± 0.53 | 0.584 | 1.62 ± 0.81 | 1.55 ± 0.53 | 0.584 |
| AV Vmax (m/s) | 1.71 ± 0.33 | 2.56 ± 1.27 | 0.000 | 1.70 ± 0.33 | 2.55 ± 1.27 | 0.000 | 1.71 ± 0.33 | 2.54 ± 1.27 | 0.001 |
| AV max PG (mmHg) | 12 ± 5 | 32 ± 33 | 0.001 | 12 ± 5 | 31 ± 33 | 0.001 | 12 ± 5 | 31 ± 33 | 0.002 |
| RVOT PSAX (mm) | 25.0 ± 7.3 | 24.4 ± 5.5 | 0.681 | 24.7 ± 7.5 | 24.5 ± 5.5 | 0.866 | 24.7 ± 7.6 | 24.5 ± 5.4 | 0.916 |
| RVIT 4CH (mm) | 21.8 ± 10.5 | 22.7 ± 4.1 | 0.692 | 21.8 ± 10.9 | 22.7 ± 4.0 | 0.698 | 21.8 ± 10.9 | 22.7 ± 4.0 | 0.698 |
| LVIT 4CH (mm) | 33.1 ± 11.6 | 36.0 ± 5.7 | 0.269 | 32.7 ± 12.0 | 36.1 ± 5.6 | 0.215 | 32.7 ± 12.0 | 36.1 ± 5.6 | 0.215 |
| RVIT/LVIT | 0.71 ± 0.38 | 0.63 ± 0.09 | 0.281 | 0.72 ± 0.40 | 0.63 ± 0.09 | 0.225 | 0.72 ± 0.40 | 0.63 ± 0.09 | 0.225 |
RV: right ventricular; RA: right atrium; LA: left atrium; LVEF: left ventricular ejection fraction; IVSd: intraventricular septum measured in diastole; LVIDd: left ventricular internal diameter in diastole; LVPWd: left ventricular posterior wall measured in diastole; LVIDs: left ventricular internal diameter in systole; FS: fractional shortening; TAPSE: tricuspid annular plane systolic excursion; MV: mitral valve; AV: aortic valve; Vmax: maximal velocity; max PG: maximal pressure gradient; RVOT: right ventricular outflow tract; PLAX: parasternal long axis view, PSAX: parasternal short axis view; RVIT: right ventricular inflow tract; 4CH: four-chamber-view; LVIT: left ventricular inflow tract.