Supplemental Table 7.
24h-ECG results of arrhythmogenic right ventricular cardiomyopathy (ARVC) and control group, 1/3, 2/3, 3/3 novel criteria fulfilled necessary for diagnosis, respectively. All dogs included.
| Parameter | ARVC: 1 of 3 novel criteria | ARVC: 2 of 3 novel criteria | ARVC: 3 of 3 novel criteria | ||||||
|---|---|---|---|---|---|---|---|---|---|
| ARVC (n = 89) | Controls (n = 42) | p-value | ARVC (n = 61) | Controls (n = 70) | p-value | ARVC (n = 36) | Controls (n = 95) | p-value | |
| Time 24h-ECG (h) | 24.4 ± 1.0 | 24.5 ± 1.1 | 0.484 | 24.4 ± 0.9 | 24.4 ± 1.1 | 0.868 | 24.3 ± 0.8 | 24.4 ± 1.1 | 0.429 |
| Mean HR (bpm) | 95 ± 24 | 85 ± 16 | 0.009 | 100 ± 26 | 85 ± 15 | 0.000 | 101 ± 29 | 88 ± 18 | 0.004 |
| VPC present | 88 (98.9%) | 37 (88.1%) | 0.013 | 61 (100%) | 64 (91.4%) | 0.030 | 36 (100%) | 89 (93.7%) | 0.123 |
| Number VPC | 1802 ± 2996 | 7 ± 11 | 0.000 | 2582 ± 3342 | 45 ± 167 | 0.000 | 2920 ± 3495 | 585 ± 1821 | 0.000 |
| Polymorphic VPC | 73 (83.9%) | 21 (56.8%) | 0.002 | 55 (91.7%) | 39 (60.9%) | 0.000 | 35 (97.2%) | 59 (67.0%) | 0.000 |
| VPC negative lead I | 36 (41.9%) | 11 (29.7%) | 0.230 | 28 (47.5%) | 19 (29.7%) | 0.063 | 20 (55.6%) | 27 (31.0%) | 0.014 |
| VPC positive lead II | 39 (45.3%) | 13 (35.1%) | 0.325 | 24 (40.7%) | 28 (43.8%) | 0.855 | 14 (38.9%) | 38 (43.7%) | 0.691 |
| VPC negative lead III | 33 (46.5%) | 14 (45.2%) | 1.000 | 27 (54.0%) | 20 (38.5%) | 0.164 | 17 (56.7%) | 30 (41.7%) | 0.195 |
| Couplets present | 68 (76.4%) | 0 (0.0%) | 0.000 | 54 (88.5%) | 14 (20.0%) | 0.000 | 36 (100%) | 32 (33.7%) | 0.000 |
| Number Couplets | 388 ± 1601 | 0 ± 0 | 0.005 | 565 ± 1913 | 2 ± 8 | 0.015 | 895 ± 2438 | 25 ± 150 | 0.001 |
| Polymorphic couplets | 27 (40.9%) | NA | NA | 26 (49.1%) | 1 (7.7%) | 0.006 | 18 (50.0%) | 9 (30.0%) | 0.133 |
| Triplets present | 38 (42.7%) | 1 (2.4%) | 0.000 | 34 (55.7%) | 5 (7.1%) | 0.000 | 26 (72.2%) | 13 (13.7%) | 0.000 |
| Number Triplets | 99 ± 403 | 0 ± 0 | 0.003 | 144 ± 481 | 0 ± 0 | 0.013 | 235 ± 613 | 4 ± 27 | 0.000 |
| Polymorphic triplets | 10 (25.6%) | 0 (0.0%) | 1.000 | 10 (28.6%) | 0 (0.0%) | 0.306 | 6 (23.1%) | 4 (28.6%) | 0.718 |
| VT present | 33 (37.1%) | 4 (9.5%) | 0.001 | 30 (49.2%) | 7 (10.0%) | 0.000 | 21 (58.3%) | 16 (16.8%) | 0.000 |
| Number VT | 96 ± 766 | 0 ± 1 | 0.421 | 140 ± 924 | 0 ± 1 | 0.209 | 235 ± 1201 | 1 ± 4 | 0.058 |
| Duration longest VT (beats) | 24 ± 31 | 7 ± 4 | 0.282 | 26 ± 33 | 9 ± 6 | 0.207 | 32 ± 37 | 9 ± 5 | 0.019 |
| HR fastest VT (bpm) | 259 ± 60 | 261 ± 52 | 0.967 | 266 ± 59 | 234 ± 52 | 0.193 | 271 ± 56 | 244 ± 59 | 0.159 |
| Polymorphic VT | 5 (15.2%) | 0 (0.0%) | 1.000 | 5 (16.7%) | 0 (0.0%) | 0.245 | 4 (19.0%) | 1 (6.3%) | 0.259 |
| R-on-T | 55 (62.5%) | 0 (0.0%) | 0.000 | 46 (76.7%) | 9 (13.8%) | 0.000 | 36 (100%) | 19 (21.3%) | 0.000 |
| Number of beats R-on-T | NA | NA | NA | 450 ± 2487 | 13 ± 25 | 0.563 | 631 ± 2805 | 21 ± 31 | 0.350 |
| R-on-T % of all beats | NA | NA | NA | 26.4 ± 68.1 | 51.9 ± 24.6 | 0.275 | 24.0 ± 72.2 | 43.1 ± 41.7 | 0.293 |
VPC: ventricular premature complexes; HR: heart rate; VT: ventricular tachycardia.