Table 2.
Intervention data by compliance status. Values are numbers (percentages) unless stated otherwise
| Participants | Compliers (n=214) | Non-compliers (n=115) | All (n=329) |
|---|---|---|---|
| Demographics | |||
| Mean (SD) age (years) | 76.4 (7.8) | 77.7 (8.1) | 76.9 (7.9) |
| Men | 144 (67) | 51 (44) | 195 (59) |
| Mean (SD) ADAS-cog score (imputed) | 21.9 (9.7) | 20.5 (9.4) | 21.4 (9.6) |
| Medical conditions* | |||
| Heart or circulatory | 102 (48) | 52 (50) | 154 (49) |
| Glyceryl trinitrate spray | 18 (8) | 13 (13) | 31 (10) |
| Lung disease | 22 (10) | 18 (17) | 40 (13) |
| Inhaler | 22 (10) | 14 (14) | 36 (11) |
| Diabetes | 38 (18) | 21 (20) | 59 (19) |
| Neurological condition | 42 (20) | 15 (15) | 57 (18) |
| Limiting joint or muscle pain | 117 (55) | 60 (58) | 177 (56) |
| Broken bones in past 6 months | 14 (6.5) | 8 (8) | 22 (7) |
| Mental illness | 65 (30) | 45 (44) | 110 (35) |
| Dose received† | |||
| Mean (SD) sessions attended (range) | 26.2 (2.1) (22-30) | 11.2 (8.0) (0-22) | 21.0 (8.7) (0-30) |
| Sit to stand: | |||
| Median (interquartile range) start weight (kg) | 4 (1.7-6) | 3 (1.4-6) | 4 (1.5-6) |
| Median (interquartile range) finish weight (kg) | 7 (0-15.1) | 6 (1-10) | 6.8 (0-12.1) |
| Median difference (95% CI): difference between start and finish weight (kg) | 4 (2.6 to 5.6) | 2.1 (0.9 to 3.2) | 3 (1.8 to 4.2) |
| Median (interquartile range) total weight lifted (kg×reps)‡ | 3460.8 (1857.3-5537.1) | 1307.5 (276-2284) | 2569.8 (1231.4-4672) |
| Median (interquartile range) arm exercises (total weight lifted)‡ | 2469.4 (1626.3-3444.2) | 1001.9 (463-1574) | 1933.5 (1105-2905) |
| Cycling: | |||
| Mean (SD) total mins low intensity | 210.5 (70.7) | 131.5 (72.6) | 186.6 (79.9) |
| Median (interquartile range) total mins high intensity | 58 (19-98) | 0 (0-18) | 38 (2-78) |
| Moderate or high exercise (total) in last session (mins): | |||
| Median (interquartile range) target No | 20 (10-20) | 15 (5-20) | 20 (10-20) |
| Median (interquartile range) actual No | 20 (10-20) | 10 (0-20) | 17 (7-20) |
| 6 minute walk test | |||
| Mean (SD) baseline 6 min walk distance (m) | 340.0 (114.0) | 315.4 (108.7) | 332.1 (112.7) |
| Mean (SD) 6 week 6 min walk distance (m) | 363.0 (118.1) | 355.8 (101.6) | 361.8 (115.3) |
| Mean difference 0-6 weeks (95% CI) in 6 min walk distance (m) | 19.6 (12.5 to 26.7) | 10.7 (−6.3 to 27.8) | 18.1 (11.6 to 24.6) |
For numbers and corresponding percentages, denominator is total in column heading unless stated otherwise.
*
Of 329 participants randomised to exercise programme arm, 317 attended pre-exercise assessment.
†
Of 329 participants randomised to exercise programme arm, 306 had resistance session data.
‡
Total weight lifted is sum of (weight lifted multiplied by number of repetitions) across all sessions.