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. 2018 May 9;11:2699–2708. doi: 10.2147/OTT.S164056

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© 2018 Du and Zhu. This work is published and licensed by Dove Medical Press Limited

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LOXL2 shows a higher expression level in glioma tissues.

Notes: (A) Representative negative staining of LOXL2 in normal brain tissue. (B) Representative high expression of LOXL2 in glioma tissue (male, 22 years old, WHO grade III). (C) RT-qPCR results of LOXL2-mRNA expression in normal brain tissues (n=8) and glioma tissues (n=13), showing a higher LOXL2-mRNA level in glioma (P<0.05). (D) The protein expression of LOXL2 was tested in 8 paired freshly resected normal brain tissues (N) and glioma tissues (T) by Western blot, and glioma LOXL2 showed a higher protein level than normal brain tissues in 75.0% (6/8) paired samples. Magnification 400×. Scale bar, 50 μm.

Abbreviations: LOXL2, lysyl oxidase-like 2; RT-qPCR, real-time quantitative polymerase chain reaction; WHO, World Health Organization.