Table S1.
Diagnostic criteria for ARMS and FE patients (Yung et al., 2003)1
| Patients | Inclusion and acute psychosis criteria | Definition |
|---|---|---|
| FE | A | Acute psychosis: psychotic symptoms above the transition cut-off (BPRS scales: any ratings of hallucination at 4 or above, unusual thought content at 5 or above, suspiciousness at 5 or above, conceptual disorganization at 5 or above) at least several times a week and persistent for more than a week. |
| ARMS | A1 | “Attenuated” psychotic symptoms: psychotic symptoms below the transition cut-off (BPRS scales: ratings of hallucinations at 2–3, unusual thought content 3–4, or suspiciousness 3–4) at least several times per week persisting for >1 week. |
| A2 | BLIPS: psychotic symptoms over the transition cut-off (BPRS scales: hallucinations ≥4, unusual thought content ≥5, suspiciousness ≥5, conceptual disorganization ≥5), but each symptom lasting <1 week before resolving spontaneously. | |
| B | Genetic risk category: first- or second-degree relative with psychotic disorder and at least two further risk factors according to the screening instrument. | |
| C | Precondition for all categories: criteria of transition to psychosis remain unfulfilled. |
Notes: ARMS patients fulfill either A1 or A2. If none of them is appropriate, criterion B must apply. Criterion C is mandatory for all subgroups of ARMS patients.
Abbreviations: ARMS, at-risk mental state for psychosis; BLIPS, Brief Limited Intermittent Psychotic Symptoms; BPRS, Brief Psychiatric Rating Scale; FE, first-episode psychosis.