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. 2018 May 9;12:1183–1193. doi: 10.2147/DDDT.S147104

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© 2018 Wang et al. This work is published and licensed by Dove Medical Press Limited

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Alignment of the initial structure (cyan) and the last snapshot (yellow).

Notes: (A) ALK^WT and alectinib; (B) ALK^G1202R and alectinib; (C) ALK^WT and JH-VIII-157-02; and (D) ALK^G1202R and JH-VIII-157-02.

Abbreviations: ALK, anaplastic lymphoma kinase; ATP, adenosine triphosphate.