Table 2.

Altered regional differences in activation during cognitive reappraisal in patients with anxiety disorder compared to healthy controls

Brain regions	MNI coordinates			SDM z score	p-value	Voxels, n	Cluster breakdown	Heterogeneity	Jackknife sensitivity
AD < HC	X	Y	Z
Left superior frontal gyrus, medial, BA 32	−2	28	38	−2.667	~0	2,489	Left superior frontal gyrus, medial, BA 8, 9, 24, 32 (464) Left anterior cingulate/paracingulate gyri, BA 32, 24 (473) Left median cingulate/paracingulate gyri, BA 24, 23, 32 (407) Left supplementary motor area, BA 6, 8, 24, 32 (212) Right median cingulate/paracingulate gyri, BA 24, 23, 32 (483) Right anterior cingulate/paracingulate gyri, BA 24, 32 (229) Right superior frontal gyrus, medial, BA 8, 9, 32 (114) Right supplementary motor area, BA 6, 8, 24, 32 (107)	ns	11 out of 11
Left inferior parietal (excluding supramarginal and angular) gyri, BA 3	−48	−28	46	−2.329	0.000002563	1,138	Left inferior parietal gyri, BA 2, 3, 40 (290) Left postcentral gyrus, BA 1, 2, 3, 4, 6, 40 (561) Left supramarginal gyrus, BA 2, 3, 40, 48 (187) Left precentral gyrus, BA 3, 4, 6 (100)	ns	11 out of 11
Left amygdala	−28	−10	−12	−1.767	0.000503182	216	Left amygdala, BA 20, 28, 34, 36 (139) Anterior commissure (41) Left inferior network (36)	Significant	9 out of 11
Left fusiform gyrus, BA 18	−26	−72	−12	−1.483	0.002632022	69	Left fusiform gyrus, BA 18, 19 (56) Left lingual gyrus, BA 18, 19 (13)	Significant	9 out of 11
Right superior parietal gyrus, BA 7	26	−74	56	−1.696	0.000781834	39	Right superior parietal gyrus, BA 7 (39)	ns	8 out of 11
Left middle frontal gyrus, orbital part, BA 11	−24	34	−16	−1.478	0.002699077	27	Left middle frontal gyrus, orbital part, BA 11 (27)	Significant	9 out of 11

Abbreviations: AD, anxiety disorder; BA, Brodmann area; HC, healthy control; MNI, Montreal Neurological Institute; ns, non-significant; SDM Z, signed differential mapping Z-value.