Table S1.

Imaging methodology quality assessment checklist (when criteria were partially met, 0.5 points were assigned)

Category 1: subjects	Score (0/0.5/1)
1. Patients were evaluated prospectively, specific diagnostic criteria were applied, and demographic data were reported
2. Healthy comparison subjects were evaluated prospectively, psychiatric and medical illnesses were excluded
3. Important variables (eg, age, gender, illness duration, onset time, medication status, comorbidity, severity of illness) were checked, either by stratification or statistically
4. Sample size per group >10
Category 2: methods for image acquisition and analysis
5. Magnet strength at least 1.5 T
6. MRI slice-thickness ≤3 mm
7. Whole brain analysis was automated with no a priori regional selection
8. Coordinates reported in a standard space
9. The imaging technique used was clearly described so that it could be reproduced
10. Measurements were clearly described so that they could be reproduced
Category 3: results and conclusions
11. Statistical parameters for significant, and important non-significant, differences were provided
12. Conclusions were consistent with the results obtained and the limitations were discussed
Total  /12