Table 1.
A |
B |
C |
||
---|---|---|---|---|
Total | No CMV infection | CMV infection | P value BvsC | |
Donor | N = 181 | N = 161 | N = 20 | |
Gender (men/women) | 73/108 | 66/95 | 7/13 | 0.6† |
Age (y) ± SD | 51.3 ± 10.1 | 41.5 ± 15.4 | 45.1 ± 18.5 | 0.3$ |
Recipient | N = 181 | N = 161 | N = 20 | |
Gender (men/women) | 107/74 | 97/64 | 10/10 | 0.4† |
Age (y) ± SD | 41.9 ± 15.8 | 51.0 ± 9.8 | 53.7 ± 12.2 | 0.3$ |
Cause of end-stage renal disease | ||||
Diabetes mellitus | 9 | 8 | 1 | 1$ |
Chronic glomerulonephritis | 76 | 70 | 6 | 0.3$ |
Polycystic kidney disease | 25 | 23 | 2 | 1$ |
Others or unknown | 71 | 60 | 11 | 0.1$ |
KTx-related parameters | ||||
AB0 incompatible yes/no | 19/162 | 16/145 | 3/17 | 0.5† |
HLA-A/B mismatches mean ± SD | 3.0 ± 1.5 | 1.9 ± 1.2 | 2.2 ± 0.8 | 0.3$ |
HLA-DR mismatch mean ± SD | 1.1 ± 0.6 | 1.1 ± 0.7 | 1.1 ± 0.6 | 0.8$ |
Cold ischemia time mean ± SD; minutes | 132.2 ± 44.1 | 132.5 ± 41.9 | 129.5 ± 60.5 | 0.7$ |
Acute cellular rejection yes/no | 41/140 | 35/126 | 6/14 | 0.4† |
Baseline CMV characteristics | ||||
CMV positive recipient (R+) | 92 | 86 | 6 | 0.048† |
CMV positive donor (D+) | 104 | 86 | 18 | 0.002† |
CMV high risk situation (yes/no) | 41/140 | 27/134 | 14/6 | <0.0001† |
†Fisher’s exact test.
$Wilcoxon rank-sum test (Mann–Whitney U Test).
y, years; HLA, human leukocyte antigen; CMV, cytomegalovirus; KTx, kidney transplantation.