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. 2018 May 8;9:917. doi: 10.3389/fimmu.2018.00917

Table 1.

Demographic and transplant-related characteristics at baseline.

A
B
C
Total No CMV infection CMV infection P value BvsC
Donor N = 181 N = 161 N = 20
Gender (men/women) 73/108 66/95 7/13 0.6
Age (y) ± SD 51.3 ± 10.1 41.5 ± 15.4 45.1 ± 18.5 0.3$
Recipient N = 181 N = 161 N = 20
Gender (men/women) 107/74 97/64 10/10 0.4
Age (y) ± SD 41.9 ± 15.8 51.0 ± 9.8 53.7 ± 12.2 0.3$

Cause of end-stage renal disease
Diabetes mellitus 9 8 1 1$
Chronic glomerulonephritis 76 70 6 0.3$
Polycystic kidney disease 25 23 2 1$
Others or unknown 71 60 11 0.1$

KTx-related parameters
AB0 incompatible yes/no 19/162 16/145 3/17 0.5
HLA-A/B mismatches mean ± SD 3.0 ± 1.5 1.9 ± 1.2 2.2 ± 0.8 0.3$
HLA-DR mismatch mean ± SD 1.1 ± 0.6 1.1 ± 0.7 1.1 ± 0.6 0.8$
Cold ischemia time mean ± SD; minutes 132.2 ± 44.1 132.5 ± 41.9 129.5 ± 60.5 0.7$
Acute cellular rejection yes/no 41/140 35/126 6/14 0.4

Baseline CMV characteristics
CMV positive recipient (R+) 92 86 6 0.048
CMV positive donor (D+) 104 86 18 0.002
CMV high risk situation (yes/no) 41/140 27/134 14/6 <0.0001

Fisher’s exact test.

$Wilcoxon rank-sum test (Mann–Whitney U Test).

y, years; HLA, human leukocyte antigen; CMV, cytomegalovirus; KTx, kidney transplantation.