Figure 2.

Frequency of K13-propeller mutations pre- and post-ACT in Kenya. Most mutations had frequencies ≤ 2%. L505F was highest in frequency pre-ACTs (9.4%), whereas N585K was highest in frequency post-ACTs (5.2%). * SNP reported in SEA, ** SNP reported in SEA but with a different amino acid, ^ SNP reported in SSA, ^^ SNP reported in SSA but with a different amino acid, and † SNP reported in both SSA and SEA. ACT = artemisinin combination therapy; SEA = Southeast Asia; SNP = single-nucleotide polymorphism; SSA = Sub-Saharan Africa.