Table 2.
Demographics and symptoms associated with acute DENV infections vs. acute CHIKV infections in index cases
| Characteristics | Acute DENV | Acute CHIKV | P value |
|---|---|---|---|
| N = 98 | N = 52 | ||
| Age in years, mean (SD) | 20.2 (15.0) | 35.8 (19.4) | <0.0001 |
| Gender, % female | 41/98 (41.8%) | 35/52 (67.3%) | 0.005 |
| Temperature > 38°C | 26/98 (26.5%) | 6/51 (11.8%) | 0.06 |
| Hospitalized | 20/98 (20.4%) | 5/52 (9.6%) | 0.14 |
| Symptoms in prior 7 days | |||
| Fever | 97/98 (99.0%) | 50/52 (96.2%) | 0.57 |
| Headache | 80/97 (82.5%) | 37/51 (72.5%) | 0.23 |
| Anorexia and nausea | 64/98 (65.3%) | 19/52 (36.5%) | 0.001 |
| Muscle/joint pain | 75/97 (77.3%) | 50/52 (96.2) | 0.006 |
| Rash | 16/97 (16.5%) | 18/52 (34.6%) | 0.05 |
| Bleeding | 8/98 (8.2%) | 2/52 (3.8%) | 0.51 |
| Vomiting | 46/98 (46.9%) | 12/52 (23.1%) | 0.007 |
| Drowsiness/lethargy | 82/98 (93.9%) | 46/52 (88.5%) | 0.58 |
| Abdominal pain | 62/97 (63.9%) | 19/52 (36.5%) | 0.002 |
| Diarrhea | 27/98 (27.6%) | 16/52 (30.8%) | 0.82 |
| Retro-orbital pain | 67/98 (68.4%) | 35/51 (68.6%) | 1 |
CHIKV = chikungunya virus; DENV = dengue virus; SD = standard deviation. Index cases with acute DENV infections were significantly younger and more likely to report anorexia and nausea, vomiting, and abdominal pain (P < 0.05). Index cases with CHIKV were more likely to be female, were older, and were more likely to report muscle/joint pain (P < 0.05). One individual with a DENV and CHIKV coinfection was excluded. Bolded text denotes statistical significance (P <0.05).