Table 3.
Performance of three diagnostic tests relative to qPCR-O150 for Onchocerca volvulus detection in skin snips
| qPCR-O150 | |||
|---|---|---|---|
| Positive | Negative | Total | |
| qPCR-MCA | |||
| qPCR-MCA positive | 200 | 5 | 205 |
| qPCR-MCA negative | 24 | 242 | 266 |
| Total | 224 | 247 | 471 |
| Sensitivity | Specificity | ||
| 89.3% | 98.0% | ||
| O150-PCR ELISA | |||
| O150-PCR ELISA positive | 127 | 0 | 127 |
| O150-PCR ELISA negative | 97 | 247 | 344 |
| Total | 224 | 247 | 471 |
| Sensitivity | Specificity | ||
| 56.7% | 100% | ||
| Microscopy | |||
| Microscopy positive | 179 | 10 | 189 |
| Microscopy negative | 45 | 237 | 282 |
| Total | 224 | 247 | 471 |
| Sensitivity | Specificity | ||
| 80% | 96% | ||