Table 3. Results of multivariate general linear model analyses with the Consortium to Establish a Registry for Alzheimer’s disease (CERAD) tests results as dependent variables and diagnosis as primary explanatory variable, while adjusting for age, sex and education.
Shown are the model-generated marginal means (SE) of the z-scores of all CERAD tests.
Variables |
Controls A | Nondeficit Schizophrenia B |
Deficit schizophrenia C | Amnestic mild cognitive imairment D | F | df | p | Partial Eta squared |
---|---|---|---|---|---|---|---|---|
VFT | 0.466 (0.093) B,C,D | -0.162 (0.149) A,C | -0.834 (0.149) A,B,D | -0.102 (0.138) A,C | 20.33 | 3/235 | <0.001 | 0.206 |
BNT high | 0.077 (0.108) | -0.072 (0.173) | -0.113 (0.172) | -0.128 (0.159) | 0.65 | 3/235 | 0.581 | 0.008 |
BNT medium | 0.218 (0.096) D | 0.025 (0.154) | 0.057 (0.154) | -0.134 (0.142) A | 1.77 | 3/235 | 0.153 | 0.022 |
BNT low | 0.140 (0.084) D | 0.276 (0.135) D | 0.096 (0.135) | -0.251 (0.125) A,B | 2.96 | 3/235 | 0.033 | 0.036 |
BNT total | 0.194 (0.085) D | 0.180 (0.135) D | 0.070 (0.135) | -0.238 (0.125) A,B | 3.08 | 3/235 | 0.028 | 0.038 |
MMSE | 0.247 (0.087) B,C | -0.154 (0.139) A,C | -0.698 (0.139)A,B,D | 0.071 (0.128) C | 10.88 | 3/235 | <0.001 | 0.122 |
WLM correct1 | +0.317 (0.094) B,C,D | -0.364 (0.150) A,C | -0.831 (0.151) A,B,D | -0.028 (0.140) A,C | 14.60 | 1/236 | <0.001 | 0.157 |
WLM correct2 | +0.354 (0.091) B,C,D | -0.312 (0.145) A,C | -0.919 (0.146) A,B,D | -0.022 (0.135) A,C | 18.76 | 1/236 | <0.001 | 0.193 |
WLM correct3 | +0.344 (0.086) B,C | -0.311 (0.136) A,C | -1.059 (0.138) A,B,D | -0.022 (0.135) C | 24.59 | 1/236 | <0.001 | 0.238 |
WLM total | +0.376 (0.086) B,C,D | -0.365 (0.136) A,C | -1.039 (0.137) A,B,D | +0.003 (0.127) A,C | 25.79 | 1/236 | <0.001 | 0.247 |
WL True Recall | +0.400 (0.090) B,C,D | -0.069 (0.143) A,C | -0.923 (0.144) A,B,D | -0.188 (0.133) A,C | 22.80 | 3/236 | <0.001 | 0.225 |
WL False Recall | -0.394 (0.090) B,C,D | +0.052 (0.143) A,C | +0.928 (0.144) A,B,D | +0.190 (0.134) A,C | 22.65 | 3/236 | <0.001 | 0.224 |
WLRecCorrect | +0.229 (0.102) C | +0.026 (0.161) C | -0.673 (0.162) A,B,D | -0.064 (0.150) C | 8.00 | 3/236 | <0.001 | 0.092 |
WLRecNoCorrect | -0.026 (0.109) | +0.065 (0.173) | -0.255 (0.175) | +0.085 (0.162) | 0.87 | 3/236 | 0.456 | 0.011 |
WLRec total | +0.213 (0.102) C | +0.065 (0.162) C | -0.667 (0.163) A,B,D | -0.064 (0.151) C | 7.72 | 3/236 | <0.001 | 0.089 |
VFT: Verbal Fluency Test. BNT: Boston Naming Test (BNT) with easy and highly frequency objects (BNT high), medium frequency objects (BNT medium) and low frequency objects (BNT low) and their sum (BNT total). MMSE: Mini-Mental State Examination. WLM: Word list memory, with three Trials including Trial 1 (WLM correct 1), Trial 2 (WLM correct 2), Trial 3 (WLM correct 3) and their total (WLM total). WLRecall True: Word List Recall, Delayed, true recall. WLRecall false: Word List Recall, Delayed, false recall. WLRecCorrect: Word List Recognition Correct Yes response. WLRecNoCorrect: Word List Recognition Correct No response. WLRec total: World List Recognition total.