Fig 4. The FC differences between pre-acupuncture and post-acupuncture in AD patients (P<0.001, with topoFDR corrected).

Regions which were significantly changed in ALFF were selected as seeds to perform the seed-based interregional correlation analysis. Increased connectivity between the right hippocampus and the left precentral gyrus was found in the AD patients when comparing post-acupuncture with pre-acupuncture.