Table 2. Regions showing decreased and increased brain activities in AD patients comparing to HCs before acupuncture.
| Brain regions | Cluster voxels | MNI coordinates(mm) | Maximum Z | ||
|---|---|---|---|---|---|
| x | y | z | |||
| SCC | 19 | 3 | 12 | -9 | 4.98 |
| MCC_R | 22 | 27 | -30 | 39 | 5.23 |
| IFG_R | 19 | 39 | 21 | 15 | 5.53 |
| SFG_R | 26 | 24 | 0 | 72 | -5.41 |
| Hippocampus_R | 31 | 27 | -12 | -6 | 4.87 |
| Postcentral_L | 34 | -15 | -30 | 78 | -4.93 |
| ITG_R | 25 | 51 | -36 | -15 | 4.71 |
P < 0.001 with topo FDR corrected. AD, Alzheimer’s disease; HC, healthy control; SCC, subgenual cingulate cortex; MCC, middle cingulate cortex; IFG, inferior temporal gyrus; SFG, superior frontal gyrus; ITG, inferior temporal gyrus.