Table 4. IRIDICA-positive and blood culture-negative detections.
PCR/ESI-MS-reported organism with blood culture negative result | No. of PCR/ESI-MS-positive, blood culture-negative samples | Medical records review |
---|---|---|
Escherichia coli | 5 | Urine culture positive for Escherichia coli/Effective antibiotic treatment against Escherichia coli |
Klebsiella pneumoniae | 3 | Urine culture positive for Klebsiella pneumoniae/Clinical diagnosis of pneumoniae/Klebsiella pneumoniae identified in aortic abscess |
Pseudomonas aeruginosa | 2 | Clinical diagnosis: sepsis from urinary tract infection |
Legionella pneumophila | 2 | Detection of Legionella pneumophila urinary antigen |
Bartonella henselae | 1 | Positive serology for Bartonella henselae |
Neisseria gonorrhoeae | 1 | Clinical diagnosis: pelviperitonitis Neisseria gonorrhoeae-related |
Neisseria meningitidis | 1 | Clinical data insufficient |
Streptococcus agalactiae | 1 | Clinical presentation compatible with Streptococcus agalactiae infection |
In 16 patients a potential pathogen was detected by the molecular method but not by MALDI-TOF. The review of clinical data and additional relevant exams from other specimens was used for the resolution of discrepancies.