Table 2. Descriptive pedigree statistics for each affected and control cohort showing average, maximum, and minimum inbreeding, number of sires, number of dams, average genetic relationship, and average 5-generation pedigree completeness index (PCI).
Cohort | Average inbreeding coefficient | Maximum inbreeding coefficient | Minimum inbreeding coefficient | Number of sires | Number of dams | Average relationship | Average PCI |
---|---|---|---|---|---|---|---|
A93/95 | 0.0824 | 0.1153 | 0.0394 | 23 | 32 | 0.1841 | 0.9994 |
C93/95 | 0.0820 | 0.1882 | 0.0300 | 129 | 159 | 0.1466 | 0.9963 |
A94/96 | 0.0834 | 0.1302 | 0.0394 | 23 | 37 | 0.1869 | 0.9992 |
C94/96 | 0.0849 | 0.1882 | 0.0300 | 140 | 183 | 0.1463 | 0.9962 |
A95/97 | 0.0837 | 0.1302 | 0.0394 | 28 | 41 | 0.1784 | 0.9988 |
C95/97 | 0.0848 | 0.1882 | 0.0310 | 154 | 204 | 0.1452 | 0.9967 |
A96/98 | 0.0875 | 0.1421 | 0.0550 | 28 | 47 | 0.1811 | 0.9985 |
C96/98 | 0.0857 | 0.1646 | 0.0310 | 178 | 238 | 0.1439 | 0.9971 |
A97/99 | 0.0851 | 0.1421 | 0.0496 | 23 | 38 | 0.1870 | 0.9985 |
C97/99 | 0.0848 | 0.1642 | 0.0368 | 149 | 187 | 0.1445 | 0.9978 |
A98/00 | 0.0875 | 0.1421 | 0.0496 | 18 | 32 | 0.2027 | 0.9988 |
C98/00 | 0.0867 | 0.1645 | 0.0368 | 130 | 158 | 0.1455 | 0.9982 |
A99/01 | 0.0838 | 0.1411 | 0.0440 | 16 | 24 | 0.2251 | 0.9997 |
C99/01 | 0.0896 | 0.1645 | 0.0448 | 105 | 118 | 0.1518 | 0.9986 |
A00/02 | 0.0908 | 0.1501 | 0.0440 | 23 | 35 | 0.2212 | 1.0000 |
C00/02 | 0.0907 | 0.1712 | 0.0325 | 132 | 175 | 0.1522 | 0.9978 |
A01/03 | 0.0898 | 0.1501 | 0.0440 | 23 | 46 | 0.2276 | 0.9997 |
C01/03 | 0.0930 | 0.1831 | 0.0325 | 161 | 230 | 0.1530 | 0.9984 |
A02/04 | 0.0907 | 0.1501 | 0.0610 | 18 | 45 | 0.2473 | 0.9997 |
C02/04 | 0.0947 | 0.1831 | 0.0325 | 159 | 223 | 0.1530 | 0.9984 |
A03/05 | 0.0917 | 0.1488 | 0.0610 | 15 | 39 | 0.2529 | 0.9997 |
C03/05 | 0.0965 | 0.1831 | 0.0375 | 145 | 194 | 0.1550 | 0.9996 |
A04/06 | 0.0994 | 0.1598 | 0.0680 | 15 | 27 | 0.2485 | 1.0000 |
C04/06 | 0.0990 | 0.1639 | 0.0505 | 112 | 134 | 0.1565 | 0.9996 |
A05/07 | 0.1022 | 0.1598 | 0.0680 | 13 | 19 | 0.2547 | 1.0000 |
C05/07 | 0.0987 | 0.1639 | 0.0505 | 82 | 94 | 0.1594 | 0.9997 |