Appendix 1—table 2. Table of Characteristics for the Malian dataset by Sl and McC genotype.
| Sl1/Sl1 | % | Sl1/Sl2 | % | Sl2/Sl2 | % | P value | McCa/McCa | % | McCa/McCb | % | McCb/McCb | % | P value | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clinical status | Uncomplicated malaria | 19 | 10.3 | 78 | 42.4 | 87 | 47.3 | 103 | 56.0 | 61 | 33.2 | 20 | 10.9 | ||
| CM | 5 | 14.7 | 19 | 55.9 | 10 | 29.4 | 0.135# | 16 | 47.1 | 15 | 44.1 | 3 | 8.8 | 0.478# | |
| Gender | M | 11 | 10.3 | 48 | 44.9 | 48 | 44.9 | 57 | 53.3 | 41 | 38.3 | 9 | 8.4 | ||
| F | 13 | 11.7 | 49 | 44.1 | 49 | 44.1 | 0.945 | 62 | 55.9 | 35 | 31.5 | 14 | 12.6 | 0.430 | |
| Ethnicity | Dogon | 21 | 11.0 | 88 | 46.1 | 82 | 42.9 | 108 | 56.5 | 66 | 34.6 | 17 | 8.9 | ||
| Non-Dogon | 3 | 11.1 | 9 | 33.3 | 15 | 55.6 | 0.448# | 11 | 40.7 | 10 | 37.0 | 6 | 22.2 | 0.078 | |
| Blood group | O | 13 | 10.0 | 63 | 48.5 | 54 | 41.5 | 68 | 52.3 | 49 | 37.7 | 13 | 10.0 | ||
| Non-O | 11 | 12.5 | 34 | 38.6 | 43 | 48.9 | 0.355 | 51 | 58.0 | 27 | 30.7 | 10 | 11.4 | 0.566 | |
| Median age | Months | 32 | IQR 20–57.5 | 31 | IQR 18–52 | 30 | IQR 17–55 | 0.927 | 30 | IQR 17–52.5 | 31 | IQR 18–54.5 | 51 | IQR 29–64.5 | 0.229 |
CM, cerebral malaria; IQR, interquartile range. Significance testing uses uncomplicated malaria as the reference group. Age: Kruskal Wallis test. #: Fisher’s exact test. All other analyses: Pearson’s χ2.