FIG. 3.
HUVEC and NuFF response to shear stress: Representative bright-field images of HUVECs (a) and NuFFs (b) seeded in the MBR treated with 1 or 12 dynes/cm2. (c) A representative impedance reading along the culture period. The resistance value at each shear stress was averaged over all trials and shows that HUVECs have a higher barrier function than NuFFs at 1 dynes/cm2 (d) and 12 dynes/cm2 (e). Scale bars are 50 μm and 200 μm. (f) Alignment of the cells in the microfluidic devices at 1 and 12 dynes/cm2. (g) Aspect ratio of the cells in the microfluidic device at 1 and 12 dynes/cm2.