Skip to main content
. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Environ Sci Pollut Res Int. 2017 Nov 15;25(17):16493–16507. doi: 10.1007/s11356-017-0149-1

Fig. 6.

Fig. 6

Differential gene expression status in the 45-month-old exposed Slovak children is shown as the analyzed IPA core comparison, where major molecular mechanism and signaling pathways are represented with the percent of genes involved in either up (red) and/or down-regulation (green), relative to the number of no overlapping genes (white), along with their − (log) p values. Molecular mechanisms of cancer showed the highest number of genes involved (335). In all cases, the majority of impacted genes does not match with the known disease and disorders in the IPA knowledgebase, which might suggest that the PCB exposure influences a discreet gene expression signature in specific pathways leading to development of disease and disorder in such exposure scenario in the later part of life