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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2018 Jan 4;24(5):973–982. doi: 10.1016/j.bbmt.2018.01.003

Table 2B.

Risk factors for grade III/IV aGvHD using Multivariable Cox regression model (N=322)

Risk Factor HR 95% CI P Reliability
HCT on Admission (< 25% vs. ≥25%) 1.37 0.77, 2.45 0.29 26%
Disease risk (Low, Intermediate, High) 0.38 16%
 Intermediate vs Low 0.79 0.40, 1.54 0.48
 High vs Low 1.28 0.71, 2.28 0.41
HLA Match 0.04 67%
 10/10 Unrelated donor vs. 10/10 Sibling 1.33 0.70, 2.50 0.38
 <10/10 Match vs. 10/10 Sibling 2.37 1.21, 4.67 0.01
RBC units (d−7 to +27): Median (> 5 vs. ≤5) 2.06 1.14, 3.73 0.02 78%
Platelet units (d−7 to +27): Median (> 2 vs. ≤2) 0.88 0.49, 1.54 0.63 5%