Figure 1. Path Models of Hypothesized Effects of Patients’ Financial Stress and Its Precursors on Quality of Life, Anxiety and Depression Symptoms, and Global Mental Health.

(A) Based on R² estimates, the model accounts for 22.1% of the variance in patients’ perceptions of their quality of life, 37.0% of the variance in the existence of financial stress as one of the top three stressors, 30.7% of the variance in the latent anxiety construct, and 54.1% of the variance in patients’ self-assessed mental health status. All of these values have associated p <0.001. The p-value for the χ² test of fit of this model to the observed data = 0.0854.

(B) Based on R² estimates, the model accounts for 21.2% of the variance in patients’ perceptions of their quality of life, 31.2% of the variance in the existence of financial stress as one of the top three stressors, 55.5% of the variance in the latent depression construct, and 52.5% of the variance in patients’ self-assessed mental health status – all having p <0.001. This model provided substantially better fit to the observed data than did the analogous model with anxiety symptoms as the mediator, having p-value for the χ² test of fit = 0.2529.