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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Crit Care Med. 2018 Jun;46(6):e508–e515. doi: 10.1097/CCM.0000000000003070

Figure 3. A-CA results in greater loss of brain antioxidants than VF-CA.

Figure 3

(A) Non-arrested shams had higher brain ascorbate levels (mean=39.1; n=3) than VF (31.7; n=11) or A-CA (28.4; n=10) rats 15 min after ROSC. ACA brain ascorbate was significantly reduced compared to VF brain ascorbate indicating greater ROS burden. (B) Assay of the total antioxidant reserve of the same brain samples were congruous: Sham (127.4 nmol ROS scavenged/mg protein), VF (84.2), and ACA (75.7). Symbols: * p<0.05 after Holm-Šídák multiple comparison adjustment.