Fig. 5. Immunoblot detection of prostate cancer cells targeted by using PBM nanoparticle and the expression of pro- and anti-apoptotic, pro-survival and proliferation markers.
Expression of (A) pro-apoptotic (BAX, BAK) and Cleaved Caspase 3 proteins (B) anti-apoptotic (BCL-2, BCL-XL) and survivin proteins (C) pro-survival and inflammatory markers (NF-kB p65, COX-2) in PC3 and PC3-R cells treated with FA-conjugated (RES or RES+DTX) for 48 h. As an internal standard for equal loading blots was probed with a GAPDH antibody for each sample.