7.
The survival curves of mice bearing MC38 xenografts following chemotherapy combined with immunotherapy treatment. When the volume of the tumor reached 500 mm3, the chemotherapeutic drugs 5-Fu/oxaliplatin and/or phosphate buffered saline (PBS) were intraperitoneally injected in the mice. The immune therapies were conducted twice on d 3 and d 7 following injection of the chemotherapeutic drugs. The survival curves of the tumor bearing mice were drawn by the Kaplan-Meier method. The tumor bearing mice were observed for 90 d after inoculation. The mice with a tumor volume of greater than 5,000 mm3 were sacrificed.