2.

Clinicopathological details of nine patients with tumor recurrence

Patient	Sex	Age	Stage	CEA	Surgery	Perioperative BT	ypN	Metastatic site	RFS (months)	Follow-up (months)	Outcome
CEA, carcinoembryonic antigen; BT, blood transfusion; RFS, recurrence-free survival; M, male; F, female; APR, abdominoperineal resection; LAR, low anterior resection; LN, lymph nodes.
1	M	66	cT3N1	34.58	APR	No	N0	Distant LN	49	66	Alive
2	M	57	cT3N2	1.28	LAR	Yes	N0	Liver	60	67	Alive
3	F	51	cT3N1	5.59	APR	Yes	N0	Lung	44	50	Alive
4	F	46	cT3N0	4.29	LAR	Yes	N0	Liver, lung	11	42	Dead
5	M	48	cT3N2	16.38	APR	Yes	N0	Local, distant LN, lung, bone	37	53	Dead
6	M	45	cT3N2	1.56	LAR	No	N0	Distant LN, lung	38	69	Alive
7	F	72	cT3N1	12.76	APR	Yes	N1a	Lung	12	39	Dead
8	F	56	cT3N2	4.34	APR	Yes	N2b	Distant LN	28	72	Alive
9	M	28	cT3N1	14.48	APR	No	N2b	Bladder, peritoneum	26	32	Dead