Figure 5.
CD11b+Dectin-2+ cells are involved in the inhibitory effect of AAV-IL-10 Mice were treated intraperitoneally with CAWS or vehicle, 2 weeks after the injection of AAV-GFP (control) or AAV-IL-10. Heart samples were obtained at day 28 after CAWS or vehicle treatment. (A) The sections were subjected to immunohistochemical staining for Dectin-2. (B) The mRNA levels of Clec4n were assessed by a real-time RT-PCR analysis (n = 4–5). (C) The population of CD11b+Dectin-2+CD45+ cells was assessed by flow cytometry (n = 7–8). Data are expressed as the mean ± SEM. *p < 0.05, **p < 0.01.