. 2018 May 16;7:85. doi: 10.1038/s41426-018-0088-z

Table 3.

Amino acid substitutions in the novel H1N1 and H3N2 reassortant isolates compared with human isolates

Lineage/subtype	Host	Virus	No. of glycosylation sites in HA	HA^a					PB2					M2	NA^c
Lineage/subtype	Host	Virus	No. of glycosylation sites in HA	138	190	225	226	228	271	590	591	627	701	31	274
EA H1N1	Human	A/Hunan/42443/2015	7	A	D	E	Q	G	A	G	R	E	D	N	Y
EA H1N1	Swine^b	Sw/GX/NNXD2023/2013	6	*	*	*	*	*	*	S	*	*	*	*	*
EA H1N1	Swine^b	Sw/GX/QZ5/2014	6	*	*	*	*	*	*	S	*	*	*	*	*
EA H1N1	Swine^b	Sw/GX/LZA3/2015	6	*	*	*	*	*	*	N	*	*	*	*	*
EA H1N1	Swine^b	Sw/GX/NN1994/2013	7	*	*	*	*	*	*	S	*	*	*	*	*
EA H1N1	Swine^b	Sw/GX/CZ7/2014	6	*	*	*	*	*	*	S	*	*	*	*	*
EA H1N1	Swine^b	Sw/GX/LB9/2014	6	*	*	*	*	*	*	S	*	*	*	*	*
EA H1N1	Swine^b	Sw/GX/BS30/2014	6	*	*	*	*	*	*	S	*	*	*	*	*
EA H1N1	Swine^b	Sw/GX/NNLX/2014	6	*	*	*	*	*	*	S	*	*	*	*	*
EA H1N1	Swine^b	Sw/GX/BB2/2013	6	*	*	*	*	*	T	*	Q	*	N	*	*
EA H1N1	Swine^b	Sw/GX/GG6/2013	6	*	*	*	*	*	T	*	Q	*	N	*	*
Early H1N1	Avian	A/duck/Schleswig/21/1979	6	*	E	G	*	*	T	*	Q	*	*	S	*
Pandemic H1N1	Swine^b	Sw/GX/DX24/2013	6	*	*	D	*	*	*	S	*	*	*	*	*
Pandemic H1N1	Human	A/California/04/2009	6	*	*	D	*	*	*	S	*	*	*	*	*
HL H3N2	Swine^b	Sw/GX/NNXD/2013	6	S	*	D	I	S	*	S	*	*	*	*	H
HL H3N2	Swine^b	Sw/GX/JGB4/2013	6	S	*	D	I	S	*	S	*	*	*	*	H
HL H3N2	Swine^b	Sw/GX/JG1/2014	6	S	*	D	I	S	*	S	*	*	*	*	H

*indicated the identical amino acids with A/Hunan/42443/2015; Sw represents swine, GX represents Guangxi

^aH3 numbering

^bisolates in this study

^cN2 numbering