Fig. 5.

Kaplan–Meier survival curves for PETTRA 2.5, Hermes 2.5, Hermes 41% and Hermes PERCIST for a) progression-free survival (PFS) and b) overall survival (OS). Both plots use PFS-derived optimal thresholds to define high and low MTV. Solid line = low-MTV group , dotted lines = high-MTV group (defined by optimal thresholds). ** p < 0.001. The table shows log-rank scores from comparison of non-progressor (N) & progessor (P) for each MTV method, with number of events, 5-year PFS ([5y-PFS) and median survival in days (Med-Surv). Log-rank scores revealed significant differences in PFS between progressors & non-progressors with all methods. No non-progressor groups reached below 50% PFS (i.e. no median survival is available)