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. 2018 Jan 20;45(3):355–364. doi: 10.1007/s10928-018-9571-3

Fig. 2.

Fig. 2

Population mean predicted HDL-C and LDL-C effects. The population mean predicted effect of fed state and meal type on HDL-C in patients treated with anacetrapib monotherapy (a top left). The population mean predicted effect of fed state and meal type on LDL-C in patients treated with anacetrapib monotherapy (b top right) or in combination with 20 mg atorvastatin (c bottom left). The population mean predicted effect of atorvastatin dose on LDL-C in patients treated with anacetrapib in combination with atorvastatin (d bottom right). Hi Fat standard high fat meal, Pt. selected patient-selected meal, Lo Fat standard low fat meal.

Adapted with permission from Krishna et al. [15]