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Predicted difference in low-density-lipoprotein cholesterol (LDL-C) from coadministration for ezetimibe/atorvastatin fixed-dose combination (FDC) tablets as a function of atorvastatin geometric mean ratio (GMR). Median prediction: solid line; 95% confidence interval: shaded region; GMR of the observed bioequivalence (BE) data and 90% confidence interval: boxes with lines.
Reproduced with permission from Vargo et al. [17]
